The San Francisco 49ers officially have a significant injury problem on their hands. Running back Christian McCaffrey is out ...

San Francisco 49ers left tackle Trent Williams found a possible silver lining in all the injuries the team is dealing with ...

The San Francisco 49ers will face the Los Angeles Rams on Sunday without wide receiver Deebo Samuel and running back ...

The NFL season is officially back, but unfortunately, that means injuries are as well. It's been just one week, but all 32 ...

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

The San Francisco 49ers are reportedly eyeing significant trade opportunities to fill critical gaps in their roster, ...

Last season, Purdy had his best season yet finishing as a finalist for MVP where he threw for 4,280 yards to go with 31 touchdowns and 11 interceptions. He was voted captain for this season as 49ers ...

The San Francisco 49ers are preparing for their Week 1 contest against the New York Jets on Monday at Levi's Stadium in Santa ...

NFC West foes San Francisco and Los Angeles face off again on Sunday. Here's what to know about one of the oldest rivalries ...

San Francisco 49ers quarterback Brock Purdy (13 ... (AP Photo/David Becker) Those injuries preceded the 49ers’ third offensive series — and the final one featuring Purdy, Kittle and Samuel.

Predictions and how to watch the 2024 NFL Week 2 matchup between the San Francisco 49ers and Los Angeles Rams.

The San Francisco 49ers stumbled in Week 2, falling to the Minnesota Vikings as 6.5-point favorites in one of the many upsets that took place in the second week ...