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The amino acid sequence of a protein encodes its three-dimensional structure and determines its ... finding desirable mutants within each library 4, and allows the characterization of many more ...
If the NMR data collection for a 120 residue protein takes 4–5 weeks on a 600 MHz spectrometer and if automated data processing takes 1 day, 120 structures can be determined in 1 year by 12 ...
More specifically, a 2021 study revealed that memory-related proteins can bind together to form droplet-like structures at postsynaptic densities. What makes these structures particularly intriguing ...
4 Soon thereafter Hassabis turned his attention to the protein ... In the subsequent years, DeepMind created the AlphaFold Protein Structure Database, which now includes over 200 million structures.
More specifically, a 2021 study revealed that memory-related proteins can bind together to form droplet-like structures at postsynaptic densities. What makes these structures particularly intriguing ...
We compute amino acid sequences predicted to fold into proteins with new structures and functions, produce synthetic genes encoding these sequences, and characterize them experimentally. I will ...