The three-dimensional shape of a protein determines its function. This is because proteins form attachments and interact with many other molecules and structures inside organisms. The shape of a ...

The amino acid sequence of a protein encodes its three-dimensional structure and determines its ... finding desirable mutants within each library 4, and allows the characterization of many more ...

“The big take-home message is that it is now possible to use computational methods to get very good models of protein structures,” said protein biochemist David Eisenberg of the University of ...

If the NMR data collection for a 120 residue protein takes 4–5 weeks on a 600 MHz spectrometer and if automated data processing takes 1 day, 120 structures can be determined in 1 year by 12 ...

Basecamp Research says it has augmented the AlphaFold2 artificial intelligence tool for predicting protein structures to create a platform that is more accurate and better at modelling small ...

This is the first systematic and mechanistic study investigating the divergent structure of protein-regulated multiphase condensates,” highlights Dr. Pandey. These findings could pave the way toward a ...

"There are relatively few RNA-only assembly structures compared to protein assembly structures in the Protein Data Bank. These studies further demonstrate the power of cryoEM for molecular ...

Scripps Research scientists discovered that some sections of the hormone-carrying molecule transthyretin (left) are in constant motion (right), which may explain why the protein can misfold and ...