Isotretinoin is indicated for nodular acne or severe acne that is unresponsive to conventional therapies. The usual dose is 0.5 to 1.0 mg/kg/day for 20 weeks, or a cumulative dose of 120 mg/kg.

Medically reviewed by Deeptej Singh, MD Nodular acne, or nodulocystic acne, is severe, inflammatory acne that causes acne ...

Patients should be informed that currently available light treatments are not recommended amongst first-line treatments for acne vulgaris, and that long-term safety data in acne are as yet unknown.