First, the myosin catalytic head binds ATP, which releases the head from actin. Second, ATP hydrolysis results in a conformational change of the catalytic head into a pre-stroke state. Third ...

No biological system has been studied by more diverse approaches than the actin-based molecular motor myosin. Biophysics, biochemistry, physiology, classical genetics and molecular genetics have ...

as actin building blocks are either added to or removed from the ends of filaments. According to the classical model, the generation of cell movement also requires the molecular motor myosin.