ICH Q6B provides expectations and a clear framework for the structural characterization of biopharmaceutical products.

This has proven useful for the structural characterization of lantibiotics, as it allows for lantibiotic precursor peptides with amino-acid substitutions to be fed to the biosynthetic machinery ...

Of 20 plasma amino acids measured, valine, leucine, isoleucine, tyrosine and phenylalanine were increased, and glycine decreased, in obese subjects compared with age- and sex-matched controls.