An AST/ALT ratio higher than 2:1 (where the AST is more than twice as high as the ALT) is a sign of alcoholic liver disease. However, a disease cannot be diagnosed by the pattern of elevation alone.

In some cases, the AST-to-ALT ratio may help your doctor diagnose certain liver diseases. ... Your doctor will speak with you about your results and what they mean.

Comparing ALT with AST levels gives your doctor more information about the health of your liver. The AST-to-ASL ratio can help your doctor figure out how severe the liver damage is and what might ...

AST levels may also be minimally elevated, but the AST:ALT ratio is usually < 1. In individuals with cirrhosis, the AST:ALT ratio may exceed 1, but is rarely, if ever, > 2.

The De Ritis ratio, defined as the ratio of serum aspartate aminotransferase (AST) to serum alanine aminotransferase (ALT) levels, effectively stratified the risk for 30-day mortality in patients ...