In a recent study published in PNAS, Zhang showed that the transcription factor DLX2 can convert astrocytes into progenitors that produce various cell types, including neurons. 3 These findings ...

Astrocytes are the largest and most prevalent type of glial cell in the central nervous system. Astrocytes contribute to formation of the blood–brain barrier, participate in the maintenance of ...

“Ben put a lot of effort into developing the cell culture protocols so that the starting astrocytes were physiological or otherwise normal,” said Tesar. “Understanding that if we could mimic at least ...

This dissertation focuses on the glial protein GFAP and Alexander disease, a severe neurological disorder primarily affecting young children. Mutations in the GFAP gene disrupt astrocyte function, ...