Although the Cvt pathway is the only known biosynthetic use of autophagy, selectivity represents an important aspect of many autophagic processes. For example, specific organelle degradation has ...

A research team has uncovered a new mechanism involving astrocytes for treating Alzheimer's disease (AD) and proposed a novel ...

Cellular homeostasis depends on the timely clearance of damaged cellular organelles and proteins via pathways including autophagy. Mitochondria and mitochondrial autophagy play a vital role in ...

Originally characterised as a hormonal and starvation response, it is now well established that autophagy has a much broader role in biology, including organelle remodeling, protein quality control, ...