The yeast cytoplasm-to-vacuole targeting (Cvt) pathway is one example of specific autophagy (see figure part b), and the only example of a biosynthetic autophagy-related pathway. The overall ...

The research team showed that ATG8, which is normally located in small cellular vesicles that mediate autophagy, is quickly relocated to the vacuole membrane upon disruption of the cell wall.

Autophagy is an evolutionally conserved cellular process to maintain homeostasis in eukaryotes. Double-membraned autophagosomes engulf cytosolic cargoes to deliver them to the lysosome or vacuole for ...

Autophagy may selectively remove damaged mitochondria ... ER, endoplasmic reticulum; STX17, syntaxin 17; TFEB, transcription factor EB; VMP1, vacuole membrane protein 1. Histology of endocrine ...