The relationship between autophagy and apoptosis is complex; autophagy constitutes an adaptive stress response that avoids cell death and suppresses apoptosis under certain circumstances, whereas ...

At the molecular level, the cross-talk between apoptosis and autophagy is manifested by the numerous genes that are shared by both pathways. These include regulatory genes such as p53 and p19ARF ...

Interaction between regulatory elements of both autophagy and apoptosis (e.g., the inhibitory interaction between BCL-2 and Beclin 1 and the interaction between LC3B and Fas) 31,32 suggests ...

Autophagy is one of two mutually antagonistic mechanisms by which cells respond to stress; the other mechanism is apoptosis, or programmed cell death . 3,4 As tumor cells up-regulate antiapoptotic ...

While autophagy and apoptosis are different processes – the former is about helping cells survive, and the latter helps remove cells in a controlled way – they can be connected.

That's not just a fun fact - autophagy plays a role in disease too. With their growing understanding of autophagy, some medical researchers, including UCSF's Jayanta Debnath, MD, believe that cellular ...

Our results revealed that inhibition of CHOP expression enhanced autophagy and reduced DTT-induced apoptosis in BRL-3A cells, whereas CHOP overexpression worsened apoptosis. Chromatin ...

A recent study published in Genes & Diseases reveals a novel role of XPR1 in promoting ovarian cancer growth by regulating ...

Tokyo Medical and Dental University. "Opening an autophagy window as the apoptosis door starts to close." ScienceDaily. www.sciencedaily.com / releases / 2020 / 09 / 200924101927.htm (accessed ...

Apoptosis and autophagy may be closely interrelated and carefully balanced. For example, if organelle damage is too extensive for autophagy to bring under control, the cell must die for the sake ...

There’s been a lot of literary discussion this year about fasting, and rightfully so. More and more research is unearthing vast benefits of fasting for people with and without diabetes, which can lead ...

Ever feel like your body needs a "deep clean"? Like your cells are screaming to get rid of all the old and damaged stuff to work better? Well, let me tell you something incredible!