B cells can control responses of myeloid cells through the release of particular cytokines (small proteins that control the growth and activity of cells in the immune system), disproving the ...
They serve multiple, often overlapping functions, from prompting the maturation of antibody-producing B cells to instigating blood vessel growth. Not surprisingly then, cytokines function both as ...
Explore diffuse large B-cell lymphoma — symptoms, causes, diagnosis, treatment options, and prevention. Learn about its types ...
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Instead, the cytokine may act through other cell populations ... “This was not what I originally expected,” said Chang, who had initially thought that B cells, which make up a majority of the splenic ...
This method was shown to successfully deplete B cells in preclinical trials without causing cytokine release syndrome (CRS) ...
No evidence for alteration in B cell cytokine profiles is available Evidence that rituximab affects T-cell activation by B cells includes reduced T-cell expression of HLA-DR, CD154 and CD69 ...
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This results in local T-cell activation and proliferation, secretion of cytokines, and the lysis of CD20-expressing B cells. The odronextamab BLA is supported by data from the open-label phase 1 ...