Actin is a major component of the cytoskeleton in yeast, plant and animal cells, but when did it evolve? The discovery of a bacterial protein that forms actin-like filaments suggests an answer.

It was thought until recently that bacteria lack the actin or tubulin filament networks that organize eukaryotic cytoplasm. However, we show here that the bacterial MreB protein assembles into ...

Studying bacterial interactions with actin is still throwing up new mysteries ... a protein that cells use to build an intracellular cytoskeleton to aid cell motility, division, and other important ...

The cytoskeleton is composed of three ... enclosed organelles came the revelation that bacteria contained structural homologs of eukaryotic actin and tubulin. This discovery led investigators ...

Many bacterial toxins have the ability to enter ... vesicular trafficking or actin cytoskeleton. Enterotoxins (cholera toxin [CT] or STb), which selectively upregulate fluid secretion are the ...

A harmful and often deadly substance made by bacteria ... the regulation of the cell's cytoskeleton, which consists of a network of polymerized actin (F-actin) filaments involved in many essential ...

In contrast, eukaryotic cells, which evolved after bacteria, have a network of filaments for support and movement. A protein known as actin forms much of this cytoskeleton, which can look like a ...

The study results showed that intracellular bacteria act to reorganize the actin cytoskeleton in circulating tumor cells (CTCs), and this promotes CTC survival by enhancing resistance to ...

More information: "A prophage-encoded actin-like protein required for efficient viral DNA replication in bacteria." Nucl. Acids Res . first published online April 27, 2015 DOI: 10.1093/nar/gkv374 ...

Inhibition of histone deacetylase leads to the reorganization of the actin cytoskeleton of dendritic ... and Staphylococcus aureus bacteria. In contrast, the treatment of BMDCs with valeric ...

In turn, the cytoskeleton relies on a type of actin protein, called filamentous or F-actin. It forms networks of thin, flexible filaments that affect the shape, stiffness, and movement of cells.

Only one thousandth of a milligram of the bacterial botulinum ... the regulation of the cell’s cytoskeleton, which consists of a network of polymerized actin (F-actin) filaments involved in ...