The tail of bacteriophage T4 is shown before (left) and after (right) binding to a host cell. Upon attachment to the bacterium, the bacteriophage pierces the host cell envelope and injects its ...

Bacteriophage T4 is a virus that infects only bacteria, in this case E. coli, a bacteria used extensively in molecular biology research. The study of bacterial viruses such as T4 is useful in ...

Research presents an assembly-line approach using bacteriophage T4 components to construct artificial viral vectors (AVVs). These AVVs have the potential to revolutionize gene therapies and ...

To bypass this obstacle, a homology atomic model of gp20 was constructed by comparing the X-ray structures of three portals from closely related bacteriophages, namely, SPP1 gp6, phi29 gp10, and P22 ...

Bacteriophage T4 therapy could therefore be engineered to benefit people with rare conditions, who often must seek out very expensive therapies — or may not have any treatment options at all.

Study design The scientists used bacteriophage T4 as a model platform to design vaccine candidates. The capsid of T4 is coated with two nonessential proteins namely Soc and Hoc.

And it doesn't specifically show a T4 bacteriophage, a virus that primarily targets and infects the bacteria Escherichia coli; it simply represents any bacteriophage.

Structural features of the 120 x 86 nm bacteriophage T4 capsid nanoshell at near-atomic resolution (Left—front view; Right —cross-section view showing empty interior).

New research shows that a needle-free mucosal bacteriophage (phage) T4-based COVID-19 vaccine is effective against SARS-CoV-2 infection.

Here we propose a new method of T4 phage purification by affinity chromatography after its modification with affinity tags (GST and Histag) by in vivo phage display. As any permanent introduction of ...