When there was unequivocal clinical or histologic evidence of liver disease, or an increase in the direct-reacting "fraction" of serum bilirubin or confirmation of a positive test for ...

Conjugated hyperbilirubinemia occurs when bilirubin, a by-product of red blood cells, builds up in the blood. This can indicate several underlying causes, such as hepatitis, cirrhosis, or biliary ...

Bilirubin is a viscous, brownish-yellow substance that is a natural byproduct of liver processes like breaking down old red blood cells. Normally, it is excreted from the body without cause for ...

Conjugation of bilirubin and delivery to the intestine doesn't necessarily lead to excretion of the substance. Neonatal intestines contain beta-glucuronidase, an enzyme capable of reducing ...