The widely used chemotherapy drug paclitaxel, commonly known as Taxol, was first extracted from the Pacific yew tree in 1963.

Scientists have now elucidated the biosynthesis pathway of this base. DNA is composed of nucleobases represented by the letters A, T, G and C. They form the basis of the genetic code and are ...

Stanford University researchers report the discovery of eight previously unknown genes that, when expressed in tobacco leaves, reconstitute the Taxol precursor baccatin III at levels matching its ...

Researchers from the Max-Planck Institute for Chemical Ecology have unraveled the complete biosynthetic pathway for strychnine, which is naturally produced by the poison nut tree (Strychnos nux ...

New findings by scientists at the RIKEN Plant Science Center (PSC) have shed first-ever light on the biosynthesis pathways of a family of phytohormones known as auxins, which play a central role in ...

Until now, researchers have been unable to characterize the stages of the melatonin biosynthesis pathway due to a lack of sensitive and selective techniques. The seven synthetic intermediates in ...

In animals, cysteine biosynthesis was thought to be created exclusively via the transsulfuration pathway, with the cystathionine β-synthase (CBS) enzyme as a key player. However, previous ...

Tsukuba, Japan—Researchers have been studying the transcription factor SREBP, a critical regulator of lipid biosynthesis ... The RHBDL4-SREBP-1c pathway, uncovered in this study, represents ...

Scientists from the Institut Pasteur and the CNRS, in collaboration with the CEA, have now elucidated the biosynthesis pathway of this base. This work has been published in the April 30th ...