The study demonstrates that the regulated secretion of mucins and insulin is biphasic, meaning a first rapid release of pre-docked granules is followed by a second, slower release of granules from a ...

The study demonstrates that the regulated secretion of mucins and insulin is biphasic, meaning a first rapid release of pre-docked granules is followed by a second, slower release of granules from ...

This investigation was undertaken to study the insulin secretory pattern and insulin responsiveness of a large number of obese subjects in an attempt to establish whether relative or absolute ...

Intensive insulin regimens effectively manage complications but biphasic premixed insulin used once- or twice-daily may be preferred. Development of BIAsp 30 presents added benefits that are reviewed.

Insulin therapy is the most effective antidiabetic therapy when dosed appropriately and has a variety of effects that may protect against the progression of β-cell dysfunction in T2DM.

To determine whether geniposide induces changes in both phases of insulin secretion, we tested the influence of geniposide on biphasic insulin secretion in INS-1 cells in the absence or presence ...

Rorsman P et al. (2000) The Cell Physiology of Biphasic Insulin Secretion. News Physiol. Sci. 15:72-77. Centers for Disease Control and Prevention (CDC) (2014) National Diabetes Statistics Report.