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thanks to a feature known as the blood-brain barrier. Bioengineers believe that they can finally work around this barrier to deliver advanced treatments for medical conditions. Early goals include ...
A new drug targeting inflammation in the brain has been shown to bolster the blood-brain barrier in mice, pioneering a potential shift in the fight against neurodegenerative diseases like Alzheimer's.
There's a bouncer in everyone: The blood-brain barrier, a layer of cells between blood vessels and the rest of the brain, kicks out toxins, pathogens and other undesirables that can sabotage the ...
Characterization of the monoFZD 4-specific WNT/β-catenin signaling surrogate, L6-F4-2. a Binding affinity of the recombinant F4-2_Fab molecule to FZD 4 CRD measured by BLI assay. Dotted lines ...
The blood-brain barrier (BBB) is a tightly interlaced system of specialized cells that creates a layered semi-permeable membrane that serves a dual purpose: it protects against toxins or pathogens ...
The blood-brain barrier (BBB) performs this vital function, but it can become “leaky.” Now, scientists at Stanford have identified therapeutic molecules that could help patch it up ...
were published in Nature Materials in a paper titled "Blood–brain-barrier-crossing lipid nanoparticles for mRNA delivery to ...
Designing BBB organoids posed a technical challenge: growing the two components—the brain ... blood vessels in the BBB. In contrast, blood vessel organoids did not express these molecules before ...
The device inside the skull opens the blood-brain barrier, repeatedly using sound waves to permeate the barrier and reach the brain tumor. IV chemotherapy is then able to reach the neurological ...
Researchers at the National University of Singapore have reported crossing the blood–brain barrier with help from a modified Lactobacillus plantarum. By delivering an appetite-regulating hormone ...