In fed-batch processes, the calculated IVCC is critical for the characterization of the culture progression and for determining process action concerning bolus feed additions. 1 Calculated changes ...

Nutrients are periodically added to bioreactors running in fed-batch mode using a bolus-feeding strategy and predetermined volumes of concentrated nutrients. These volumes are subsequently ...

Each infant underwent a 6-h monitoring, during which he/she was fed twice via an orogastric tube. One meal was given as a 10-min bolus: milk was poured into a syringe attached to the feeding tube ...