Fifty years of outstanding neuroscience research studies have revealed many secrets of how drugs of abuse affect and change ...

Researchers argue that "we may need to reevaluate the causal assumptions that underlie brain disease models of addiction." ...

Brain mapping showed that mind-altering drugs work with multiple neurotransmitter systems. The mapping showed expected relationships, such as the link between MDMA and its well-known target, the ...

By Andrew Jacobs If you had to come up with a groovy visualization of the human brain on psychedelic drugs, it might look something like this. The image, as it happens, comes from dozens of brain ...

A review of the recent evidence suggests that GLP-1 drugs, such as semaglutide, could protect brain health and cognitive function by reducing inflammation.

Getting drugs to the brain is difficult. The very thing designed to protect the brain's environment — the blood-brain barrier (BBB), tightly packed cells that prevent most substances from ...

All drugs, especially biologics, have great difficulty penetrating the brain due to the blood-brain barrier. The blood-brain barrier is a layer of cells lining the brain’s blood vessels that ...

It makes sense then that a drug that modulates the appetite will influence the brain. But it turns out that semaglutide also plugs into physiological processes that are far removed from metabolism.