To date, only two types of cannabinoid receptor have been identified, the CB1 receptor which was cloned in 1990 and the CB2 receptor which was cloned in 1993. ... (cAMP). A naturally ...

Cannabis binds to the so-called Cannabinoid receptor 1 (CB1 receptor), one of the most common receptors in our brain. CB1 receptors serve as switches that can turn various biological processes on ...

The endocannabinoid system is the body’s system that regulates an array of other systems in the body. It works to maintain homeostasis by the use of receptors, cannabinoids, and metabolic pathways ...

That discovery gave arise to this latest finding, of CB1's malleability. See, the molecules that switch CB1 on—THC and other cannabinoids—are about 100 times smaller than the receptor they ...

High CB1 receptor individuals, who are already near saturation with novelty, might find the extra endocannabinoid activity in their amygdala disorienting and overwhelming enough to produce anxiety.

The CB1 receptor is responsible for the intoxicating effect of cannabis. However, it appears to act also as a kind of 'sensor' with which neurons measure and control the activity of certain immune ...

Physical activity had a remarkably similar effect to the over-expression of CB1 receptors. Mice that were genetically altered to be missing the genes for this receptor, however, were highly ...

A team of scientists led by Professor Zhi-jie Liu at the iHuman Institute of ShanghaiTech University has determined the 3-dimensional molecular structure of the agonist-bound human cannabinoid ...

There are approximately 113 cannabinoids that have been isolated from cannabis, and receptors have been found in mammals, birds, fish, and reptiles. The receptors are members of the G-protein coupled ...

There are genetic variations in the density of active CB1 receptors, with low baseline CB1 receptor activity leading to high novelty-seeking. Boredom exists without frequent novelty stimulation.