Scientists identify CCL2 signalling pathway that triggers endothelium to permit extravasation of cancer cells. genprowebdirectory Sign in. Welcome! Log into your account. your username. your ...

Original publication: Monika Wolf et al., 2012. Endothelial CCR2 signaling induced by colon carcinoma cells enables extravasation via the JAK2-Stat5 and p38MAPK pathway, Cancer Cell, 07/2012. Contact: ...

This study elucidates the complex interplay between macrophages and CFs in the MI microenvironment, highlighting the role of the IFN-β-IFNAR-p-STAT1 signaling pathway as a critical barrier to ...

The transformation of a healthy cell into a cancerous one often comes with a slew of cellular signaling changes. These changes change both the inside activities of the cell, as well as the environment ...

Inhibition of IFN Signaling Enhances Reprogramming: Blocking the IFN signaling pathway or depleting macrophages reduces STAT1 activation and facilitates cardiac reprogramming, indicating potential ...