Naive CD4 and CD8 T cells give rise to effector and long-lived memory T cells after activation by antigen. This paper provides evidence that memory CD4 T cells, similar to their CD8 counterparts ...

Memory CD4 + T cells infiltrating the skin following VacV infection were predominately Ly6C + effector memory (T EM) cells, which expressed core two O-glycans, identified via the monoclonal ...

Some CD4+ T cells become memory cells after encountering a pathogen and becoming activated. Memory cells help the body recognize and respond more quickly in future encounters with the same invader.

Single-cell transcriptome landscape of circulating CD4+ T cell populations in autoimmune diseases. Cell Genomics , 2024; 100473 DOI: 10.1016/j.xgen.2023.100473 Cite This Page : ...

A study published in Nature identifies a pathogenic subset of CD8+ memory T-cells that promote airway tissue inflammation and recurrent respiratory diseases through an effector molecule. The role ...

All markers (CD45RO, CD45RA, CD27, CD28, CCR7, and CD127) of the T-cell differentiation process, from naive to effector memory T cells, were present in the cluster of differentially expressed markers.

The results are published in Immunity in a paper titled “Prolonged Interleukin-2Rα Expression on Virus-Specific CD8 + T Cells Favors Terminal-Effector Differentiation In Vivo.”. The team, led ...

Before this study, it was unclear how both effector and memory cells could come from the same parent T cell. An unstable protein, lost without translation. As a first clue, ...

image: During viral infection, total m 6 A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T cell expansion ...

CD4+ are helper T cells that help the activity of other immune cells by releasing cytokines. The cytokines prime the maturation of B cells, which become plasma cells and produce antibodies to ...

Aging is known to be a risk factor for the biological changes that create the dangerous buildup of plaque in arteries called atherosclerosis, and aging also induces a buildup of memory CD8 T cells ...