"CD4+ T cells can exist in a naive or memory state, can exhibit polarization to a Th1, Th2, Th17, or Tfh phenotype, or can be regulatory T cells," says lead author of the study Yoshiaki Yasumizu.

Zhuo, C., et al. (2025). Single-cell sequencing reveals the expansion and diversity of T cell subsets in the bone marrow ...

Immunologists at UNIGE have revealed a previously unknown anti-tumor role of CD4 T lymphocytes, marking a breakthrough that ...

In the fight against cancer, immunotherapy—which aims to boost the body's natural defenses against cancer—is experiencing ...

Melatonin is known to influence CD4+ T cell polarization, while hypocretin suppresses inflammatory monocyte production, which is linked to atherosclerosis.

Human immunodeficiency virus type 1 (HIV-1) infection is characterized by a rapid and profound loss of peripheral-blood CD4+ T cells, followed by a spontaneous but transient recovery in CD4+ T ...

A new study, published recently in Nature Communications, offers the first-ever map of which parts of the Chikungunya virus ...

The body's first line of defense against tuberculosis (TB) involves immune cells that suppress lung inflammation instead of ...

In HIV infection, however, a T cell subtype called the central memory CD4+ T cell appears to enter the cell cycle and undergo apoptosis—cellular suicide—in vast numbers.

A T cell count is a blood test that measures the number of T cells, which are white blood cells that fight disease. It’s also known as a thymus-derived lymphocyte count, T lymphocyte count, or ...