The researchers first compared 4 gene-editing platforms to establish SF3B1 mutant cell lines: CRISPR-Cas9 editing, AAV HDR editing, base editing and prime editing. Prime editing was shown to be more ...
During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together ...
Researchers using CRISPR-Cas9 gene editing tools have discovered that while this technology can enhance T cell cancer therapies, it may also lead to unintended chromosomal loss in the edited immune ...
A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed, resolving a major bottleneck to using the gene-editing tool CRISPR-Cas9 in many ...
No patients have received Casgevy, CRISPR Therapeutics and Vertex Pharmeceuticals’ recently approved sickle cell gene therapy ...
11don MSN
Doudna codeveloped the revolutionary gene-editing technology known as CRISPR-Cas9. Now it’s leading to cures to some of the ...
Mission Bio explains how single-cell multiomics can help researchers overcome the challenges of heterogeneous editing ...
CRISPR Therapeutics' first therapy is called Casgevy. It treats sickle cell disease (SCD) and beta thalassemia, both rare inherited illnesses that affect the function of a person's red blood cells. It ...
Researchers show how stop codon readthrough plays a key role in the cell cycle, with implications for cancer cell ...
In a new study published in the Journal of Cell Science, Associate Professor at the Department of Biochemistry, Sandeep ...
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