Trisomy is a genetic condition characterized by the presence of an extra chromosome. This means that the affected person has ...

The CRISPR-Cas9 system provides researchers a powerful tool for manipulation of cells to create disease models, reporter cell lines, cell therapy tools, and approaches for novel pathway discoveries.

A Ph.D. graduate student in biomolecular engineering at UC Santa Cruz, with a background in computer science and mathematics, ...

The replication of potentially harmful adenoviruses can be significantly reduced in human cells in cell culture by using the so-called CRISPR-Cas9 system ("gene scissors"). This method, which is ...

New research has found a novel target with therapeutic potential for metastatic eye melanoma—an aggressive eye cancer—with ...

CRISPR, short for CRISPR-Cas9, ... Rather than using immune cells, like humans do, bacteria use CRISPR. ... One big reason human germ-line editing has been avoided is that future generations ...

The second tool is the CRISPR-Cas9 system, which allows easy and precise editing of any region of the genome. When it comes to traditional immortalized cell lines, such as HeLa or HEK293, cutting with ...

This novel SNA was tested across human and mouse cell lines; it successfully delivered the cargo needed to generate the CRISPR-Cas9 machinery while retaining its bioactivity and gene-editing ...

As an innovator in human cell technology, iXCells uses CRISPR-Cas-9 to knock-in genetic elements (e.g., reporters, exon duplication, overexpression), knock-out genes (e.g., frameshift, stop codon ...

During protein synthesis, or translation, genetic information transcribed in the cell's mRNA directs the stringing together ...

CRISPR gene editing means a cure for sickle cell disease is on the horizon. However, the life-changing treatment is likely to remain out of reach for most of those who could benefit.