Adoptive cell therapy based on ex-vivo expanded tumor-infiltrating lymphocytes (TILs) has historically been most effective in ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions—but there is always room ...

Researchers from the University of Eastern Finland, Aalto University and the University of Oulu have developed a new ...

Crispr-Cas9 has the power to significantly benefit ... It can be ethical for scientists to experiment on themselves. Such studies should at least sometimes be permitted, and certainly should ...

When the CRISPR Cas9 protein is added to a cell along with a piece of guide RNA, the Cas9 protein hooks up with the guide RNA and then moves along the strands of DNA until it finds and binds to a ...

Cas9, the first Cas protein repurposed for cutting DNA, introduces double-strand breaks that recruit DNA repair machinery. Despite its successes, the CRISPR-Cas9 system has several limitations, ...

Genome editing has advanced at a rapid pace with promising results for treating genetic conditions-but there is always room for improvement.

Researchers have developed a machine learning model that predicts Cas9 proteins that can be tailored with designer properties for therapeutic use.

In this experiment, Rothamsted Research used CRISPR differently from the standard approach. Instead of introducing Cas9 and the guide RNA using particle bombardment or other direct delivery ...

Crispr Therapeutics is an emerging gene editing company focused on the development of Crispr/Cas9-based therapeutics. The company's proprietary platform specializes in clustered regularly ...