Functional regeneration of the damaged heart therefore does not usually take place. Divisions of cardiac muscle cells are extremely rare. However, when this happens, it is associated with the ...

We have found that exosomes and the cargo they contain are crucial mediators of stem cell-based heart regeneration, and we believe this might lead to an even more refined therapy using the 'active ...

Sadek and his colleagues wondered whether forcing mitochondria to continue to consume glucose might stymie DNA damage and, in turn, extend the window for heart cell regeneration. To test this idea, ...

Members of Theme Six are developing stem cell and cellular reprogramming strategies to treat cardiovascular diseases such as infarction in situ. The goal is to use viral vectors to induce ...

With the progression of heart regeneration, these cells were permanently installed in the muscle tissue and made their contribution to the restoration of cardiac function. The Max Planck ...

The research, published in the journal Cell Reports ... Again, inhibition of BMP7 reduced cardiomyocyte regeneration following cardiac injury, whereas its induction accelerated the regeneration ...

And this, it turns out, could be key to unlocking heart cell regeneration. “It is known that animal species capable of regenerating their hearts primarily use sugars and glycolysis as fuel for h ...

Researchers at the Max Planck Institute for Heart and Lung Research in Bad Nauheim, have identified a stem cell population responsible for this regeneration. Hopes are growing that it will be ...

The study advances the quest for an optimized cell therapy for heart regeneration and can facilitate the development of new drugs for heart disease. If your heart fails, you might be administered ...

Dr. Kevin Watt, team leader of the Heart Regeneration and Disease Laboratory ... who discovered that specialized cells could be reprogrammed back to immature stem cells, Watt and his collaborators ...

Dr. Kevin Watt, team leader of the Heart Regeneration and Disease Laboratory ... who discovered that specialized cells could be reprogrammed back to immature stem cells, Watt and his collaborators ...