HCM and DCM are among the most common inherited heart diseases. Both can cause serious problems like heart failure and sudden ...

A team at CNIC has developed an innovative gene therapy to treat arrhythmogenic right ventricular cardiomyopathy type 5 ...

THERE is general agreement that the membrane process activates the contractile mechanism in muscle; but up to the present all efforts to find quantitative relations between the electrical and ...

Cardiomyocytes consist of a complex membrane system that is subjected to high mechanical stress during heart muscle contractions. The so-called T-tubule network within the cells, which consists of ...

Numerous motor and structural proteins compose a highly ordered structure known as the sarcomere, the basic unit of muscle contraction in heart and skeletal muscles. Sarcomeric myosin heavy chain ...

Her research is focused on the mechanism of sarcomere proteins in heart muscle contraction. She aims to understand how troponin, specifically troponin I (TnI), contributes to the dynamic thin filament ...

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Heart Rate Increase in rate of contraction of cardiac muscle - cardiac output increases Decrease in rate of contraction of cardiac muscle - cardiac output decreases Breathing Rate Smooth muscle of ...

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Muscle is a soft tissue composed of elongated cells (muscle fibres) that produce force and motion through contraction. Involuntary cardiac and smooth muscles are responsible for contraction of the ...