At the surface, the immune response to a flu virus is simple. Some cells recognize the pathogen and send a signal to the ...

Elucidation of the mechanisms of macrophage to foam cell differentiation will help to steer us in the right direction with regards to managing atherosclerosis.

More information: Panpan Jiang et al, Dedicator of cytokinesis 8 (DOCK8) mutation impairs the differentiation of helper T cells by regulating the glycolytic pathway of CD4+ T cells, MedComm (2024).

T-bet is a transcription factor, one of the control proteins in the cell nucleus that can turn specific groups of genes on ...

While investigating a pathway involved in stem cell differentiation, researchers at UC Santa Barbara found that rather than forming an assembly line or rigid structure, all the proteins involved ...

This study reported that pasteurized Akkermansia muciniphila (pAKK) promotes the differentiation of intestinal microfold cells (M cells) and ...

Researchers have removed mitochondria from cells to better study their functions in regulating cell death, differentiation ...

“These data represent a major breakthrough for the large-scale, GMP compliant manufacture of patient-derived MSCs for therapeutic uses,” said Dr. Cynthia Bamdad, CEO of Minerva Biotechnologies, “and ...

Scientists created a model of the human pain pathway in a dish by connecting four separate brain organoids. The feat should help them understand sensory disorders like those affecting pain perception.

Driving rhabdomyosarcoma into differentiation through targeted transformation of tumor cells by Leibniz-Institut für Alternsforschung - Fritz-Lipmann-Institut e.V. (FLI) ...

Study: DOCK8 mutation disrupts helper T cell differentiation via glycolytic pathway regulation by Sichuan International Medical Exchange and Promotion Association ...

Recent research published in MedComm highlights how mutations in the Dedicator of Cytokinesis 8 (DOCK8) gene impair the differentiation of helper T cells by affecting their glycolytic metabolism ...