Organoids are made to model human organs and are promising for research and therapy, but there are limitations to their ...

Hypoxia-driven gene and protein changes enhance epithelial-to-mesenchymal transition, remodel the extracellular matrix, drive drug resistance, support cancer stem cells and aid evasion from immune ...

Hypoxia, when cells are deprived of oxygen, is a key feature of cancer and other diseases including arthritis. While it's well-known that oxygen deprivation changes how cells express DNA ...

The nitrate-nitrite-NO pathway is emerging as an important mediator of blood flow regulation, cell signaling, energetics and tissue responses to hypoxia ... against IR injury in the heart ...