Here we focus on the transformation assay, which scientists first used to identify oncogenes and tumor suppressors and study their affect on cell cycle progression. Even more important will be ...

The stages of the cell cycle (G1: Gap 1, S: DNA synthesis, G2: Gap 2, and M: mitosis) are indicated. Tumor suppressors act to maintain checkpoints (arrows) whereas oncogenes allow for checkpoints ...

Pancreatic cancer’s deadly resilience may be tied to extrachromosomal DNA, which allows tumor cells to rapidly adapt to ...

leukemic oncogenes that increase cell proliferation (class 1) and those that block the normal process of cellular differentiation (class 2). Research in animal models has led to a growing ...

Anti-oncogenic drugs - In order to grow, tumor cells produce chemical growth factors by switching on oncogenes. Many tumors rely on a mutation of the RAS oncogene in order to develop. Scientists ...

Every day, billions of cells in your body divide, helping to replace old and injured cells with new ones. And each time this ...

Scientists suggest understanding ecDNA’s role in pancreatic cancer could potentially guide future strategies for making ...

This protein helps control cell differentiation, immune system function, and cancer progression. This newly published review highlights its molecular complexity and clinical significance.

The researchers can identify infected mice that develop leukemia, isolate the white blood cells and ... requires the cooperation between different oncogenes for disease development (a concept ...