A chromosomal abnormality occurs when there is an incorrect number of chromosomes, an incorrect amount of DNA within a chromosome, or chromosomes that are structurally flawed. These abnormalities ...

An example of a balanced structural change is the Philadelphia chromosome translocation previously described. In that case, although genetic information was rearranged into an abnormal gene ...

[44] Combining a limited karyotype with the more objective microarray data will allow for a clearer interpretation for any disease-causing chromosome abnormalities, if any, in the fetus undergoing ...