Tonic Generalized-Clonic seizures: These entail an abrupt loss of consciousness, which is followed by a tonic phase (muscle stiffness) and a clonic phase (rhythmic contractions) of the muscles.

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The company should report data from two phase III studies by year end 2025 ... for depression and in primary generalized tonic-clonic seizures. A “pipeline in a molecule” approach is unfolding ...

Lacosamide displayed efficacy in animal models of partial-onset, pharmacoresistant and generalized tonic-clonic seizures, as well as status epilepticus. Pharmacokinetic studies of lacosamide in ...