The collagen-induced arthritis (CIA) mouse model is the most commonly studied autoimmune model of rheumatoid arthritis. Autoimmune arthritis is induced in this model by immunization with an ...

Blocking TNF-α with a soluble TNF-receptor fusion protein or with monoclonal antibodies also ameliorated disease activity in mice with type II collagen-induced arthritis. 23,24 Rheumatoid ...

The new study showed mice bred to have a genetic predisposition to gut permeability also developed signs of severe arthritis. A different mouse model, engineered to develop collagen-induced ...

Details of the presentation: Poster Title: DC-9476, a novel selective BRD4 (BD2) inhibitor targets key inflammatory arthritis pathways and is highly efficacious in the collagen induced arthritis ...

In vivo tests showed that the combination nanohybrid Ce-MSCNV approach successfully treated and prevented RA in a mouse model of collagen-induced arthritis (CIA) by relieving the primary symptoms ...

Significant alterations in decal microbiome diversity and composition were observed in collagen-induced arthritis (CIA) mice before visibly apparent arthritis, with intestinal inflammation and ...

Why Mediterranean Cuisine Is More Than Just a Diet — And Why People Love It To get to the bottom of things, Kuhn and her colleagues made use of the collagen-induced arthritis (CIA) model in mice ...

A protein involved in blood clotting (fibrin), also plays an important role in the development of rheumatoid arthritis ... genetically engineered mice with collagen-induced arthritis of the ...

The immune cell restricted guanine nucleotide exchange factor (GEF) and scaffolding protein VAV1 plays a key role in mediating T-cell receptor (TCR) and B-cell receptor (BCR) activity and signaling.