Gene sequencing studies have uncovered mutations in key oncogenes responsible for colorectal cancer (CRC) development. CRC tumors exhibit significant heterogeneity, and a subset of tumors harbor other ...

Researchers from Japan report that they have characterized gene mutations in colorectal cancer (CRC) tumors with high tumor mutation burden that lack mutations in the major oncogenes. Their ...

Colorectal cancer (CRC), a type of cancer ... decipher their role in the carcinogenesis of tumors lacking major driver oncogenes. Giving further insight into their work, in a study published ...

How is a normal cell transformed into a cancerous cell? The proteins involved in cell division events no longer appropriately drive progression from one cell cycle stage to the next. Cells that ...

"Based on our research, we recommend that individuals at high risk of colorectal cancer monitor ... of vitamin D — such as the regulation of oncogenes (mutated genes that can lead to cancer ...

Colorectal cancer (CRC), or bowel cancer ... and a hemoglobin immunoassay. KRAS is a proto-oncogene found to be mutated in around 40 % of all CRC cases. 11 A proto-oncogene is a normal gene ...

Colorectal cancer (CRC), a type of cancer ... of cells that harbors numerous gene mutations distinct from the driver oncogenes. The researchers thus speculate that these TMB-high tumors rely ...