The complex tumor microenvironment (TME) in osteosarcoma is emerging as a critical factor in disease progression and ...

When the macrophages’ ability to consume dying cancer cells or Upd3 production was decreased, tumor growth was significantly ...

Scientists have made an important discovery to date in the study and treatment of BRCA1-deficient cancers and PARP inhibitor resistance.

In vivo CAR T cell generation is a pioneering immunotherapy approach that reprograms the immune system to fight cancer and ...

For roughly 400 years, microscopes have allowed us to observe increasingly smaller details. Today's most advanced instruments ...

An international team of researchers from Australia and the United States has developed an artificial intelligence (AI) tool ...

With immunotherapy increasingly making it out of the lab and into hospitals as a viable way to treat serious conditions like ...

HER2 tumor marker tests are used to determine whether breast cancer is HER2 positive or negative. A person is a candidate for ...

Instead of extracting T-cells and engineering them in a lab, researchers have delivered mRNA directly into circulating immune ...

Aussie researchers have used CRISPR gene editing tools to “armor” chimeric antigen receptor (CAR) T cells to activate additional cancer-fighting proteins at the tumor site, enabling them to target ...

Researchers present a new method to safely and preferentially generate CAR T cells directly inside the body using targeted lipid nanoparticles that deliver mRNA directly to T cells. The approach ...

If the complex is mutated or silenced, tumor cells can become resistant to the therapy and continue to proliferate. “This is a crucial first step to providing an intellectual framework to ...