Medically reviewed by Johnstone M. Kim, MD A coloboma is a missing piece of tissue in a person's eye. It is a congenital condition (meaning one you are born with) that can affect any part of the ...

Colobomas are congenital defects of ... In all cases the person should be told about the possibility of complications if there is an optic nerve coloboma, namely, visual loss via retinal ...

The congenital defects most commonly associated with colobomas are cleft lip, bony defects ... The deeper the excavation produced by the coloboma, the higher is the risk of retinal detachment ...

The principal congenital abnormalities of the optic disc that ... Peripapillary choroidal neovascularisation has been described in association with optic nerve coloboma. 18 Retinal detachment ...

A coloboma of the choroid is characterized by congenital absence of part of the retinal pigment epithelium and choroid. It appears clinically as a prominent white zone within the ocular fundus ...

Depending on when and where this defect occurs, ocular colobomas may be present in any part of the eye, such as the iris, retina, lens, optic nerve, or eyelid. Chorioretinal colobomas result from ...

Amar Agarwal Development of the eye is a fascinating subject. Simultaneous invagination of the optic vesicle and the optic stalk creates the fetal fissure inferonasally, which then closes ...

One form of Leber congenital amaurosis, LCA2, is caused by a defect in a retinal pigment epithelial gene, RPE65. Could a gene-replacement therapy efficaciously and safely treat LCA2?

Cause of congenital nystagmus found Date: September 12, 2019 Source: Netherlands Institute for Neuroscience - KNAW Summary: Researchers have overturned the long held view that congenital nystagmus ...

Leber congenital amaurosis (LCA) begins to damage the retina and cause vision loss in the first few months of a baby’s life. It affects 2 to 3 out of every 100,000 newborns.

When you have an inherited retinal dystrophy (IRD), a mutation in your genes changes the way your retina is able to work. While these disorders are considered to be rare, there are many different ...