First, a few basic thoughts on corneal epithelial wound healing. The healing of an epithelial defect requires epithelial cell migration, adhesion and mitosis. The epithelial cells must migrate ...

On the outer edge of the cornea are stem cells, called limbal epithelial cells, that have the potential to become any other ...

during SMILE surgery may create microchannels that allow epithelial cells to migrate into the corneal stroma and lead to EI. This finding challenges the traditional understanding that EI is ...

CALEC (Cultivated autologous limbal epithelial cells) procedure for stem cell transplant in eye procedures is safe and feasible, showing improved corneal surfaces or vision. Cultivated autologous ...

“When limbal stem cells (LSCs) become dysfunctional or deficient, the cornea is unable to maintain its surface epithelial integrity and LSC deficiency (LSCD) develops,” the authors wrot ...

Since it’s on the frontline of potential hazards from the outside world, the cornea features a population of limbal epithelial stem cells, which repair minor damage to keep the surface smooth ...

In a pioneering study, stem-cell-derived corneal implants improve sight for patients with severe vision impairment, offering a potential breakthrough for treating limbal stem cell deficiency.

The cornea is the clear, outermost layer of the eye. It's outer border, the limbus, contains a large volume of healthy stem cells called limbal epithelial cells, which maintain the eye's smooth ...

Scientists created corneal epithelial cell sheets (iCEPS) produced from human-induced pluripotent stem cells (iPSC) for this treatment. In an attempt to restore vision by repopulating the vital ...

The treatment, called a cultivated autologous limbal epithelial cell transplantation -- or CALEC -- can help restore surface corneal epithelial cells, which can be destroyed after chemical burns ...

In these instances, the cornea is permanently damaged ... In this procedure — known as "cultivated autologous limbal epithelial cell transplantation" — doctors take stem cells from the ...