The nonprofit eye bank Eversight has partnered with Emmecell, a clinical-stage biotechnology company, to advance therapies involving donor corneal epithelial cells for treatment of eye disease ...

KALA Bio completes enrollment in CHASE trial, advancing KPI-012 for treating persistent corneal epithelial defects. Topline ...

When a person's cornea is damaged, the injury can deplete the limbal epithelial cells. As a result, the surface of the eye develops permanent damage -- a condition called limbal stem cell deficiency.

CALEC (Cultivated autologous limbal epithelial cells) procedure for stem cell transplant in eye procedures is safe and feasible, showing improved corneal surfaces or vision. Cultivated autologous ...

X-irradiated corneal and conjunctival epithelial cells exhibited typical senescence phenotypes, i.e., flattened morphologies, increased SA-β-gal activity, decreased cell proliferation, and ...

These cells formed a multilayer structure and expressed key markers of corneal epithelium, including tumor protein 63 (p63), keratin-12, keratin-3, and mucin-16.

These cells were then transformed into a thin, transparent sheet of cobblestone-shaped corneal epithelial cells. During the surgical procedure, ...

“When limbal stem cells (LSCs) become dysfunctional or deficient, the cornea is unable to maintain its surface epithelial integrity and LSC deficiency (LSCD) develops,” the authors wrote.

Novel stem cell therapy repairs 'irreversible' corneal damage in clinical trial Date: March 4, 2025 Source: Mass Eye and Ear Summary: Results from a phase 1/2 clinical trial of a novel stem cell ...

Eye injuries that damage the cornea are usually irreversible and cause blindness. But a new clinical trial has repaired this damage in patients thanks to a transplant of stem cells from their ...

When a person's cornea is damaged, the injury can deplete the limbal epithelial cells. As a result, the surface of the eye develops permanent damage -- a condition called limbal stem cell deficiency.