NSAIDs work on a chemical level. They block the effects of special enzymes -- specifically Cox-1 and Cox-2 enzymes. These enzymes play a key role in making prostaglandins. By blocking the Cox ...

For a general summary overview, the major branching pathways that lead from arachidonic acid to the eicosanoids are shown in Figure 5. Note that the COX enzymes are positioned under one major ...

By inhibiting the COX pathway, aspirin diverts arachidonic acid ... have increased activity of LTC 4 synthase, the rate-limiting enzyme in the cysteinyl LT synthesis, in their bronchial biopsy ...

A novel PET imaging approach can effectively quantify a key enzyme associated with brain inflammation, according to research published in the March issue of The Journal of Nuclear Medicine.

One of the key pathways regulating intestinal homeostasis is the wnt ... they ultimately develop into carcinomas is associated with high expression of the cyclooxygenase enzyme COX-2, leading to ...

Enzymes can be involved at every step in a reaction pathway. At each step, the molecule is transformed into another form, due to the presence of a specific enzyme. Such a reaciton pathway can ...