In a recent study, FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells ...

FMI researchers have shed light on how intestinal organoids form crypts, the pockets that house stem cells for gut ...

These Lgr5+ cells were located at the very bottom of glands, or crypts, in the intestinal lining. However, in the last decade, problems with this model began to appear. Deleting the Lgr5+ cells in ...

In the intestinal epithelium, cells proliferate in glandular pockets termed the crypts of Lieberkühn. In the 1970s, two competing theories emerged for where in the crypt these all-important, ...

In a recently published Science paper, 1 his team described how they developed a biomaterial tissue scaffold that allows intestinal stem cells to self-organize into organoids with patterned crypt-like ...

Researchers have found that the small intestine grows in response to pregnancy in mice. This partially irreversible change may help mice support a pregnancy and prepare for a second.