HPA axis suppression results in decreased circulating adrenocorticotropin ... Systemic absorption of calcineurin inhibitors is associated with the development of lymphomas and cutaneous malignancies.

In a previous post, I discussed the connection between the mind and the skin. In that article, I called for patients and clinicians to become more aware of the relationship between cutaneous and ...

The HPA axis is a complex neuroendocrine system that helps regulate the body’s response to stress. It coordinates interactions between the hypothalamus, pituitary gland, and adrenal glands.

Clascoterone cream 1% caused mild, reversible hypothalamic-pituitary-adrenal axis suppression under maximum-use exposure in patients with acne vulgaris, according to a study.“The FDA looked at ...

This is good because the HPA axis is responsible for your stress response. When you exercise by walking, you calm your nerves, which can make you feel less stressed.

Importantly for clinically relevant biology, this was associated with prolonged dysregulation of the neuro-hormone system that manages stress, called the hypothalamic-pituitary-adrenal, or HPA, axis.

In their recent CMAJ Practice article on intranasal corticosteroids, Drs. Fowler and Sowerby1 stated that this therapy is not associated with hypothalamic–pituitary–adrenal (HPA) axis suppression.