Cytokine receptor structure. ... The receptors are essentially high-affinity molecular complexes that initiate and propagate signals, beginning the cytokine-mediated communication between cells.

BRCA DNA-repair proteins interact with a molecular complex that is also responsible for regulating the immune system. When certain players in this pathway go awry, autoimmune disorders arise. An ...

Switching off the cytokine storm Date: September 14, 2023 Source: European Molecular Biology Laboratory Summary: Researchers provide essential insights on the molecular activation of the MAP ...

Cytokines are molecular messengers released by cells to regulate cell interactions and communications. As potent and complex immune mediators, they may either promote tumor growth and spread or ...

In mapping out the molecular pathway between elevated cytokines in the body and chemical changes in the brain, ... a series of structures that block most substances.

Molecular biologists and biochemists these days are focusing an increasing share of their investigations on the activities of a class of small peptide messenger molecules called cytokines. The ...

Cytokines change structure of estrogen receptor In recent years, many researchers have been working to understand the underlying mechanisms of resistance to hormone therapy in breast cancer.

In a new paper published in Science, EMBL Grenoble researchers provide essential insights on the molecular activation of the MAP kinase p38α, the final switch triggering the inflammatory response.