A breakthrough assay is advancing how researchers observe gene expression in real time. Named QRIVTA (quantitative real-time ...

Scientists at St. Jude Children's Research Hospital have reconciled two closely related but contentious mechanisms underlying ...

No longer a mere assistant who carries out the commands of DNA, RNA takes the lead in emerging therapeutics.

Every living cell transcribes DNA into RNA. This process begins when an enzyme called RNA polymerase (RNAP) clamps onto DNA. Within a few hundred milliseconds, the DNA double helix unwinds to form ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

With the long-term goal of creating living cells from non-living components, scientists in the field of synthetic biology ...

The sequence of base pairs in DNA determines the genetic code, which is read in triplets to specify the amino acid sequence of proteins. The complementary nature of base pairing allows for the ...

The tumor suppressor p53 is a transcription factor that controls the expression of hundreds of genes. Emerging evidence suggests that the p53-induced RNA-binding protein ZMAT3 is a key splicing ...