Another important purpose of DNA methylation is the formation of the chromatin structure, which enables a single cell to grow into a complex multicellular organism made up of different tissues and ...

DNA methylation inhibits gene expression in animal cells, probably by affecting chromatin structure. Biochemical studies suggest that this process may be mediated by methyl-specific binding ...

Taken together, these results are consistent with a model in which DNA methylation triggers formation of a hypoacetylated, closed chromatin structure that precludes binding of critical ...

Researchers at the Francis Crick Institute have revealed insight into why embryos erase a key epigenetic mark during early ...

Fig 4. Diagram of the gene-set enrichment analysis on DNA methylation data. The upper panel depicts the transcription factor binding sites (TFBS) within 1 kB of differentially methylated loci ...

The brain is ever changing in structure and function as a result ... being transcribed into RNAs and translated into proteins. DNA methylation is a very important part of the control of gene ...

DNA and RNA methylation, initially thought to operate as distinct pathways, have been shown to interact closely, shifting our understanding of gene regulation. A team of researchers from the ...

DNA methylation is an example of one of the many mechanisms of epigenetics. Epigenetics refers to changes in how your body “reads” your DNA. They don’t change the actual DNA sequence.

A new study has been published in Nature Communications, presenting the first comprehensive atlas of allele-specific DNA methylation across 39 primary human cell types. The study was led by Ph.D ...

This method focuses on how random certain chemical tags on DNA become over time. The team compared this new measurement, called methylation entropy, to existing methods and found it performed just ...