Alignment of DNA and protein sequences is a basic tool in the study of evolutionary, structural and functional relationship among macromolecules. Present sequence alignment methods are somewhat ...

“In contrast, by comparing species that are more closely related, such as other mammals, we can find much more DNA sequence alignment.” Pennacchio and Shyam Prabhakar are the principal authors ...

The Smith-Waterman algorithm is widely used for pairwise DNA sequence alignment. The computation, consisting of looking for pattern in very long strings of the DNA alphabet, is very demanding. Using ...

This involves overlapping the ends of the fragments because the current DNA sequencing technology is unable to read the entire genome sequence at once. The correct alignment of the DNA segments is ...

The GENESYS project, which was granted £0.5m in funding from Innovate UK, applied Optalysys’s unique optical processing technology to perform large-scale DNA sequence alignment. The collaboration with ...

Through sequence alignment with increasingly strict criteria ... but may also influence the local topology of the DNA, thereby controlling access to their associated gene. Several clusters ...

by linking the four nucleotide bases comprising DNA—A, T, C, and G—into a particular genetic sequence. Making these sequences is time-consuming and expensive, though, and the longer your ...