When DNA sequencing first broke onto the scene in the 1970s, one method shone brighter than even Sanger sequencing. However, this method is now almost obsolete. What was it and what happened to it? In ...

DNA sequencing improved by slowing down Date: September 21, 2015 Source: Ecole Polytechnique Fédérale de Lausanne Summary: Scientists have developed a method that improves the accuracy of DNA ...

This concept lies at the core of the DNA sequencing methods. Genomics is a relatively new field; in fact, the first DNA sequences were only obtained less than half a century ago in the early 1970s.

But, although these methods can differ, sometimes radically, in how they obtain the sequence of DNA, they're all fundamentally constrained by the chemistry of DNA itself, which is remarkably ...

Biomedical engineers have devised a method for making future genome sequencing faster and cheaper by dramatically reducing the amount of DNA required, thus eliminating the expensive, time ...

Many life-saving drugs directly interact with DNA to treat diseases such as cancer, but scientists have struggled to detect how and why they work—until now. In a paper published in the journal ...

“If you can watch an enzyme move one base pair at a time, that immediately suggests a new way to sequence DNA not based on its chemistry but on its nanomechanics.” The method developed by ...

Scientists may soon have a cheaper alternative to current methods of DNA sequencing, thanks to new research by Professor of Physics Xinsheng Sean Ling and his group published in July's issue of ...

The method, which uses nanopores to read individual nucleotides, paves the way for better – and cheaper – DNA sequencing. DNA sequencing is a technique that can determine exact sequence of a DNA ...