New research has identified cannabis-derived terpenes—compounds that give plants their distinctive aroma—as effective ...

Weight loss drugs like Ozempic deliver more health benefits than expected. In a study published in the journal Life, ...

Learn how caffeine cycling can restore energy, improve performance, and prevent tolerance using 4 approaches from experts and ...

We have been exploring the potential of the neuromodulator, adenosine, to reduce excessive dopamine signaling that contributes to the development and persistence of psychostimulant abuse. Dopamine’s ...

Adenosine is a short-acting endogenous molecule that is a purine nucleoside. The half-life is 6 seconds. Adenosine receptor activation results in multiple different actions depending on the location.

Poly adenosine diphosphate-ribose polymerase (PARP) inhibitors, a class of targeted anticancer therapies, prevent genetic ...

The reaction product is adenosine diphosphate (ADP), and the phosphate group either ends up as orthophosphate (HPO 4) or attached to another molecule (e.g. an alcohol). Even more energy can be ...

We are experts in the PPi-Adenosine Pathway, where the ENPP1 enzyme generates inorganic pyrophosphate (PPi), which regulates mineralization, and adenosine, which controls intimal proliferation (the ...

In intact mouse models, adenosine significantly reduced and DPCPX significantly increased the power of harmaline-induced tremor compared with baseline tremor in the same mouse (P <0.05 for both).