The ~1 Megadalton L-shaped protein complex is the largest protein assembly of the respiratory chain and now the largest asymmetric membrane protein assembly solved to date. The respiratory chain ...

These complex, macromolecular machines are collectively known as the respiratory chain. The structure of the largest protein complex in the respiratory chain, that of mitochondrial complex I ...

Complex I is the first and largest enzyme of the respiratory chain and has a central role in cellular energy production through the coupling of NADH:ubiquinone electron transfer to proton ...

Several protein complexes, termed respiratory enzyme complexes I, II, III, and IV, take part in the energy conversion system, the electron transport chain. Here, we will determine highly accurate ...

Ben Engel at the Biozentrum of the University of Basel were able to create high-resolution images of the respiratory chain directly inside cells at a resolution never achieved before. "Our data ...

Approximately 350 different gene disorders have been shown to substantially impair mitochondrial respiratory chain function, an essential process for making energy to power our cells. Respiratory ...