2003 ). For example, when expressed in the Drosophila brain, Tau protein—which forms neurofibrillary tangle pathology in AD—causes adult onset, progressive neurodegeneration, truncated lifespan and ...

More than 40 Drosophila melanogaster genes have been ... loss of the mouse orthologue in the brain has been shown to cause neurodegeneration, and loss-of-function mutations in the human orthologue ...

The brain is the part of the central nervous system ... A complete inventory of the Drosophila visual system classifies about 53,000 neurons into 732 types. The shapes and connections of all ...